if statement help

If InStr(Text1.Text, "1" Or "2" Or "3" Or "4") Then
Me.Caption = "works"
Else
Me.Caption = "not"
End If

need this working

or what i defo need is

if any alphabet keyword is found even 1 then match found please help
If InStr(Text1.Text, "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz") Then
Me.Caption = "works"
Else
Me.Caption = "not"
End If